prikaz prve stranice dokumenta Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase
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Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase
Croatian journal of food science and technology, 9 (2017), 1; 57-65. https://doi.org/10.17508/CJFST.2017.9.1.08
Strelec, Ivica; Burić, Petar; Janković, Irena; Kovač, Tihomir; Molnar, Maja

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Strelec, I., Burić, P., Janković, I., Kovač, T. i Molnar, M. (2017). Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase. Croatian journal of food science and technology, 9. (1), 57-65. doi: 10.17508/CJFST.2017.9.1.08

Strelec, Ivica, et al. "Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase." Croatian journal of food science and technology, vol. 9, br. 1, 2017, str. 57-65. https://doi.org/10.17508/CJFST.2017.9.1.08

Strelec, Ivica, Petar Burić, Irena Janković, Tihomir Kovač i Maja Molnar. "Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase." Croatian journal of food science and technology 9, br. 1 (2017): 57-65. https://doi.org/10.17508/CJFST.2017.9.1.08

Strelec, I., et al. (2017) 'Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase', Croatian journal of food science and technology, 9(1), str. 57-65. doi: 10.17508/CJFST.2017.9.1.08

Strelec I, Burić P, Janković I, Kovač T, Molnar M. Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase. Croatian journal of food science and technology [Internet]. 07.06.2017. [pristupljeno 03.04.2025.];9(1):57-65. doi: 10.17508/CJFST.2017.9.1.08

I. Strelec, P. Burić, I. Janković, T. Kovač i M. Molnar, "Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase", Croatian journal of food science and technology, vol. 9, br. 1, str. 57-65, Lipanj 2017. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:109:443755. [Citirano: 03.04.2025.]

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Podaci o radu
Naslov (engleski)Inhibitory effect of coumarin derivatives on apple (cv. Idared) polyphenol oxidase
AutorIvica Strelec
AutorPetar Burić
AutorIrena Janković
AutorTihomir Kovač
AutorMaja Molnar
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Prehrambeno-tehnološki fakultet Osijek
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Prehrambena tehnologija
Znanstveno / umjetničko
područje, polje i grana		PRIRODNE ZNANOSTI
Kemija
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Biotehnologija
Sažetak (engleski)
Inhibitory effect of 32 coumarin derivatives (20 Schiff bases, 5 thiosemicarbazides, 5 thiazolidinones, and their precursors,7-hydroxy-4-methylcoumarin and 4-methylcoumarin-7-yl hydrazine carboxylate) on partially purified apple polyphenol oxidase was investigated. Thirteen coumarin derivatives inhibited polyphenol oxidase (5 Schiff bases, 5 thiosemicarbazides,1 thiazolidinone, 4-methyl-7-hydroxycoumarin and 4-methylcoumarin-7-yl hydrazine carboxylate), while 19 derivatives showed no effect on enzyme activity. The most effective inhibitors were thiosemicarbazides, with 4-methyl-1-(2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetyl) thiosemicarbazide (compound C23) being the most prominent inhibitor (IC50 = 10.45 µM). The importance of thiosemicarbazide moiety as crucial structure element for strong apple PPO inhibition was confirmed by its cyclisation to thiazolidinone bearing the same substituents as corresponding thiosemicarbazide. Capture of the sulphur atom of thiosemicarbazide group within tiazolidinone ring caused significant loss of inhibitory effect against apple PPO.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - međunarodna recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaCroatian journal of food science and technology
Brojčani podacivol. 9, br. 1, str. 57-65
p-ISSN1847-3466
e-ISSN1848-9923
DOIhttps://doi.org/10.17508/CJFST.2017.9.1.08
URN:NBNurn:nbn:hr:109:443755
Datum objave publikacije2017-06-07
URL dokumentahttps://hrcak.srce.hr/182642
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Imenovanje-Bez prerada 4.0 međunarodna (CC BY-ND 4.0)
Datum i vrijeme pohrane2025-03-26 15:19:54