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master's thesis
Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom
2019. urn:nbn:hr:109:186414
Smolić, Ivana
Josip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
Department of Food and Nutrition Research
Sub-department of Nutrition

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Smolić, I. (2019). Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom (Master's thesis). Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY. Retrieved from https://urn.nsk.hr/urn:nbn:hr:109:186414

Smolić, Ivana. "Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom." Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2019. https://urn.nsk.hr/urn:nbn:hr:109:186414

Smolić, Ivana. "Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom." Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2019. https://urn.nsk.hr/urn:nbn:hr:109:186414

Smolić, I. (2019). 'Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom', Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, accessed 02 February 2025, https://urn.nsk.hr/urn:nbn:hr:109:186414

Smolić I. Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom [Master's thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY; 2019 [cited 2025 February 02] Available at: https://urn.nsk.hr/urn:nbn:hr:109:186414

I. Smolić, "Prediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom", Master's thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, Osijek, 2019. Available at: https://urn.nsk.hr/urn:nbn:hr:109:186414

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Metadata
TitlePrediktori smanjene koštane mase u djece i adolescenata s anoreksijom nervozom
Title (english)Predictors of Reduced Bone Mineral Density in Children and Adolescents with Restrictive Anorexia Nervosa
AuthorIvana Smolić
MentorInes Banjari (mentor)
MentorOrjena Žaja (komentor)
Committee memberIvica Strelec (predsjednik povjerenstva)
Committee memberInes Banjari (član povjerenstva)
Committee memberOrjena Žaja (član povjerenstva)
Committee memberDaniela Čačić Kenjerić (član povjerenstva)
GranterJosip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
(Department of Food and Nutrition Research)
(Sub-department of Nutrition)
Osijek
Defense date and country2019-03-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Nutrition
Dietotherapy
Abstract
Cilj rada bio je utvrditi prediktore smanjene koštane mase (SKM) u djece i adolescenata s anoreksijom nervozom (AN), uzimajući u obzir endotipe. Retrospektivna studija s prospektivno prikupljenim podacima obuhvatila je 197 hospitaliziranih pacijenata od kojih je 65 % s restriktivnim tipom, 25 % ima bulimičko-purgativni, a 10 % nespecifični poremećaj (EDNOS). Nije utvrđena razlika u učestalosti SKM obzirom na endotip, no potvrđeno je kako u trenutku hospitalizacije pacijenti već imaju SKM (r=0,531, p<0,01). Dob pacijenata (14,9 ± 2,5 godina) u trenutku hospitalizacije je potvrđena kao neovisni čimbenik rizika za SKM (41,1 % veći rizik kod starijih pacijenata). Tjelesna masa (TM) u trenutku hospitalizacije je direktno povezana s gustoćom kostiju (r=0,531, p<0,01) i TM je neovisni čimbenik rizika za SKM: rizik opada za 9,6 % po svakom kilogramu TM više u trenutku hospitalizacije te za 5,7 % po svakom kilogramu TM više prije postavljanja dijagnoze. Interesantno je kako dulja primjena nutritivne potpore (po danu) za vrijeme hospitalizacije neovisno smanjuje rizik za SKM za 8,4 %. Rezultati potvrđuju SKM koja se pogoršava s duljim trajanjem AN, neovisno o endotipu te naglašavaju potrebu za ranim otkrivanjem i adekvatnim tjelesnim oporavkom kako bi se spriječile dugoročne posljedice, od fraktura do osteoporoze.
Abstract (english)
The aim was to determine predictors of reduced bone mass (RBM) in children and adolescents with anorexia nervosa (AN), with consideration of endotypes. Retrospective study with prospectively data collection enrolled 197 hospitalized patients, 65 % with restrictive type, 25 % with purgative type and 10 % with Eating Disorder Not Otherwise Specified. Prevalence of RBM did not differ between endotypes. However, at the time of hospitalization patients already had RBM (r=0.531, p<0.01). Patients age at hospitalization (14.9 ± 2.5 years) is an independent risk factor for RBM (41.1 % higher risk with older age). Body mass at hospitalization directly correlates with bone density (r=0.531, p<0.01) and is another independent risk factor for RBD. The risk drops by 9.6 % per each kg of body mass more at hospitalization and by 5.7 % per each kg body mass more before the diagnosis. Interestingly, longer nutritional support during hospitalization independently reduces the risk of RBM by 8.4 % per day. The results confirm RBM, which worsens with AN duration, regardless of the endotype. In addition, the results emphasize the need for an early diagnosis and adequate physical recovery in order to prevent long-term consequences, from fractures to osteoporosis.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:109:186414
Study programmeTitle: Food Science and Nutrition
Study programme type: university
Study level: graduate
Academic / professional title: magistar/magistra inženjer/inženjerka nutricionizma i znanosti o hrani (magistar/magistra inženjer/inženjerka nutricionizma i znanosti o hrani)
Type of resourceText
File originBorn digital
Access conditionsOpen access
Terms of useLicence In copyright icon
Created on2019-03-18 17:45:49