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undergraduate thesis
Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova
2022. urn:nbn:hr:109:663576
Rušiti, Ilmi
Josip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
Department of Applied Chemistry and Ecology
Sub-department of Biochemistry and Toxicology

Cite this document

Rušiti, I. (2022). Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova (Undergraduate thesis). Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY. Retrieved from https://urn.nsk.hr/urn:nbn:hr:109:663576

Rušiti, Ilmi. "Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2022. https://urn.nsk.hr/urn:nbn:hr:109:663576

Rušiti, Ilmi. "Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova." Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, 2022. https://urn.nsk.hr/urn:nbn:hr:109:663576

Rušiti, I. (2022). 'Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova', Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, accessed 12 April 2024, https://urn.nsk.hr/urn:nbn:hr:109:663576

Rušiti I. Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova [Undergraduate thesis]. Osijek: Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY; 2022 [cited 2024 April 12] Available at: https://urn.nsk.hr/urn:nbn:hr:109:663576

I. Rušiti, "Utjecaj sastojaka hrane na apsorpciju i metabolizam lijekova", Undergraduate thesis, Josip Juraj Strossmayer University of Osijek, FACULTY OF FOOD TECHNOLOGY, Osijek, 2022. Available at: https://urn.nsk.hr/urn:nbn:hr:109:663576

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Metadata
TitleUtjecaj sastojaka hrane na apsorpciju i metabolizam lijekova
Title (english)Food Components Influencing Absorption and Metabolism of Drugs
AuthorIlmi Rušiti
MentorTomislav Klapec (mentor)
GranterJosip Juraj Strossmayer University of Osijek
FACULTY OF FOOD TECHNOLOGY
(Department of Applied Chemistry and Ecology)
(Sub-department of Biochemistry and Toxicology)
Osijek
Defense date and country2022-06-14, Croatia
Scientific / art field,
discipline and subdiscipline		BIOTECHNICAL SCIENCES
Food Technology
Abstract
Neke namirnice sadrže komponente koje mogu stupati u interakcije s brojnim lijekovima i na taj način pojačati ili smanjiti intenzitet djelovanja tih lijekova, samim time i utjecati na efikasnost terapije. Za metabolizam lijekova zaslužni su enzimi (CYP3A4, CYP1A2, glutation S transferaza) i transportni proteini (P-glikoprotein). Komponente hrane koje utječu na farmakokinetiku lijekova, inhibiraju ili induciraju navedene enzime i transportne proteine. Namirnice koje su bogate kompleksnim fitokemikalijama (sok od grejpa, kantarion i povrće) imaju veliki potencijal stvaranja ovakvih interakcija, stoga je nakon konzumacije ovakvih namirnica potrebna konzultacija s liječnikom te potencijalna prilagodba doze lijeka.
Abstract (english)
Some foods contain components that can interact with many medications and may thus increase or decrease the intensity of action of these drugs, and therapy efficacy. Enzymes (CYP3A4, CYP1A2, glutathione S-transferase) and transport proteins (P-glycoprotein) are responsible for drug metabolism. Food components that affect the pharmacokinetics of drugs inhibit or induce these enzymes and transport proteins. Foods rich in complex phytochemicals (grapefruit juice, St. John's wort, and vegetables) have a great potential to create these interactions, so after consuming such foods consultation with physician and a potential dose adjustment might be neccesary affect.
Keywords
Keywords (english)
Languagecroatian
URN:NBNurn:nbn:hr:109:663576
Study programmeTitle: Food Technology
Study programme type: university
Study level: undergraduate
Academic / professional title: sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije (sveučilišni/a prvostupnik/prvostupnica (baccalaureus/baccalaurea) inženjer/inženjerka prehrambene tehnologije)
Type of resourceText
File originBorn digital
Access conditionsAccess restricted to students and staff of home institution
Terms of useLicence In copyright icon
Created on2022-06-21 07:20:14